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Dogs + Medications

  • Deracoxib (brand name Deramaxx®) is a nonsteroidal anti-inflammatory drug (NSAID) used in dogs after surgery to reduce the pain associated with surgery (e.g., orthopedic and dental surgeries), as well as for the treatment of osteoarthritis. Like other NSIADs, deracoxib can affect the gastrointestinal tract with side effects. Use of other NSAIDs or corticosteroids should be avoided while your dog is taking deracoxib. Your veterinarian will do periodic blood tests to check liver and kidney function if your dog is taking deracoxib for extended periods.

  • Desmopressin is administered into the eye or is given as an injection and is used off label to treat diabetes insipidus and von Willebrand disease. Give as directed by your veterinarian. Side effects are uncommon but may include irritation upon application to the eye. Do not use in pets that are allergic to it or pets that are prone to blood clots, such as those with heart disease. If a negative reaction occurs, please call your veterinary office.

  • Dexamethasone is given on and off label, by mouth or injection, to treat various inflammatory, autoimmune, and adrenal gland conditions. It can also be used off label as a diagnostic test. Common side effects include increased drinking, urination and/or appetite, dull/dry haircoat, weight gain, pot-bellied appearance, muscle weakness, panting, vomiting, or diarrhea. Do not use in pets that are allergic to it, have systemic fungal infections, diabetes, or stomach or intestinal ulcers, or are taking NSAIDs. It should not be used in rabbits or in surgical pets. If a negative reaction occurs, please call your veterinary office.

  • Dextromethorphan is given by mouth and is used off label to treat compulsive behaviors and occasionally used to treat cough. Side effects are uncommon but may include vomiting, diarrhea, decreased appetite, sleepiness, drooling or anxiousness. Do not use in pets that are allergic to it. If a negative reaction occurs, please call your veterinary office.

  • Diazepam is given by mouth, injection, or into the rectum and is used off label to treat anxiety, seizures, tense muscles, or decreased appetite. Give as directed by your veterinarian. Side effects include sleepiness, increased appetite, incoordination, weakness, agitation, drooling, and aggression. Do not give to cats by mouth, and do not use in pets that are allergic to it or other benzodiazepines, or in pets with severe liver disease. If a negative reaction occurs, please call your veterinary office.

  • Diazoxide is given by mouth and is used off label to treat low blood sugar associated with insulin-producing tumors of the pancreas. Give as directed by your veterinarian. Common side effects include drooling, lack of appetite, vomiting, and diarrhea. Do not use in pets that are allergic to it or thiazide diuretics, or in pets with low blood sugar due to anything other than a tumor. If a negative reaction occurs, please call your veterinary office.

  • Diethylstilbestrol is given by mouth and is used off label to treat urinary incontinence. Give as directed by your veterinarian. Side effects are uncommon when using a low dose, but may include mild vaginal spotting. It should not be used in pets that are allergic to it, in females with estrogen-sensitive tumors, in pets with anemia or low white blood cell counts, or in food production animals. If a negative reaction occurs, please call your veterinary office.

  • Difloxacin is given by mouth or as an injection, and is used to treat certain bacterial infections. Side effects are uncommon but may include nausea, vomiting, lack of appetite, and diarrhea. Do not use in pets that are allergic to it, in young or growing animals or in cats. If a negative reaction occurs, please call your veterinary office.

  • Digoxin is used off label and is given by mouth or injection to treat certain abnormal heart rhythms and certain types of congestive heart failure. Common side effects include vomiting, diarrhea, lack of appetite, weight loss, tiredness, or behavior changes. Digoxin should not be used in pets that are allergic to it, in pets that already have too much digoxin in the bloodstream, or in pets with certain arrhythmias such as ventricular fibrillation or in cats with hypertrophic cardiomyopathy. If a negative reaction occurs, please call your veterinary office.

  • Diltiazem is given by mouth as a tablet, capsule, or compounded liquid, and is used off label to treat abnormal heart rhythms, high blood pressure, and other heart conditions. Common side effects include a slow heart rate in dogs and vomiting in cats. This medication should not be used in pets with hypersensitivity, severely low blood pressure, lung congestion, or certain abnormal heart rhythms. If a negative reaction occurs, please call your veterinary office.